科研动态

兽药的不合理使用可导致动物产品及环境中兽药残留超标，从而对公共卫生安全构成威胁。QuEChERS法是一类快速、简便、经济、高效、耐用和安全的样品前处理方法，常用于植物产品农药检测。通过持续优化，目前该方法开始在动物产品兽药残留检测中得到应用。本文综述了QuEChERS法的特点，探讨了该方法在畜禽产品或样品兽药残留检测中的优化与应用。与植物样品相比，动物相关样品基质复杂，脂肪含量较高，因此需要对QuEChERS法进行优化。常用的优化方式包括提取液优化、脱水盐优化和吸附剂优化。目前QuEChERS法在畜禽肌肉、内脏、鸡蛋、牛奶及相关产品以及尿液、粪便等环境样品兽药残留萃取中得到应用。随着与其他提取净化方法的连用以及自动化提取装置的不断更新，未来QuEChERS法会得到持续优化与发展，其提取效率和净化效果将进一步得到提高，并将在动物产品残留检测中发挥重要作用。

Optimization and Application of QuEChERS in Detection of Veterinary Drug Residues 

The abuse of veterinary drugs would lead to excessive veterinary drug residues in animal products and environment，posing a threat to public health. The QuEChERS，which is quick，easy，cheap，effective，rugged and safe，is a pretreatment method for samples and usually used to detect pesticide in plant products. At present，the method with continuous optimization has been applied in the detection of veterinary drug residues in animal samples. In the paper，the characteristics of the method were summarized，its optimization and application in the detection of veterinary drug residues in livestock and poultry products or samples were discussed. Animal samples were with complex matrix and higher fat content compared to plant samples，so the method should be optimized by common means including the optimizations of extraction solution，dehydration salt and adsorbent. At present，the QuEChERS has been applied in the extraction of veterinary drug residues in animal muscle，viscera，eggs，milk and related products，as well as urine，feces and other environmental samples. With continuous use of other extraction and update of automatic extraction units，the QuEChERS would be continuously optimized and developed in the future，and its extraction efficiency and purification effect would be further improved to play an important role in detection of veterinary drug residues in animal products.

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