科研动态

传染性法氏囊病病毒（infectious bursal disease virus，IBDV）新型变异株正在我国广泛蔓延，给商品肉鸡群和蛋鸡群带来了新的威胁。本研究对一个疑似发生非典型传染性法氏囊病的地方品种雪山草鸡群进行了RT-PCR检测，并对分离的3株毒株进行了基因测序及序列分析。结果显示，引起该鸡群发病的病原是IBDV新型变异株，属于A2dB1基因型；这3个毒株的VP2高变区编码蛋白上含有IBDV变异株的特征性氨基酸，也具有IBDV新型变异株的独特氨基酸。结果提示，我国地方品种鸡群中也有IBDV新型变异株的流行，现有的部分商品化IBDV疫苗已不能有效预防IBDV新型变异株的流行。

Identification of Novel Variant Strain of Infectious Bursal Disease Virus in Xueshan Chicken

Novel variant strains of infectious bursal disease virus（IBDV）have been spreading widely in China，posing a new threat to commercial broilers and layers. In the study，a local variety of Xueshan chicken with suspected atypical IBD was detected by RT-PCR，gene sequencing and sequence analysis were then conducted for the three isolates. The results showed that the disease was caused by novel variant strain of IBDV that belongs to A2dB1 genotype；in addition to the characteristic amino acids of variant strain，the unique amino acids of novel variant IBDV were also contained in the hypervariable region of VP2 encoding proteins of the three isolates. It was indicated that the novel variant IBDV could not be effectively controlled by some current commercial vaccines，as it has been spreading in local chicken in China.

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